In a long-term study of the health of the people of in the United States, the U.S. Public Health Service documented the chances of developing heart disease among various groups, in the population. Long before any symptoms appeared, epidemiological research could identify high-risk groups. The highest risk factors occur in males, over 35, cigarette smoking, high blood pressure, high levels of certain blood fats and a family history of cardiovascular disorders.

Other researchers have added to th...
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